The new Genetics cluster consists of ten pathways that explore the expansive field of genetics, from Mendel’s landmark studies with pea plants to modern-day applications.

The cluster is divided into four themed tours: Chromosomes, which explores the fundamentals of eukaryotic chromosomes, mutations, and viral chromosomes; Cellular Reproduction, which dives into the essential functions of mitosis and meiosis; Mendelian Inheritance, which covers the genotypes, phenotypes, and the discoveries made by Gregor Mendel; and Non-Mendelian Inheritance, which provides insight into the many other factors that play into the expression of genes.

Chromosomes

1. Eukaryotic Chromosomes

This pathway provides an overview of the general characteristics of a eukaryotic cell and explores how their genomic content is organized by examining key features of eukaryotic chromosomes.

2. Chromosome Variation

This pathway explores ploidy, variations in the number and structure of chromosomes, and the role that chromosome variations play in agriculture and evolution.

3. Viral Chromosomes

This pathway highlights key features of viral genomes and how viruses are grouped according to the Baltimore classification system.

Cellular Reproduction

1. Cellular Reproduction

Heritable information provides the basis for the continuity of life. This pathway explores the process of cellular reproduction in prokaryotes and eukaryotes, and how genetic information is passed on to newly formed cells.

2. Mitosis

This pathway examines how eukaryotic cells divide by mitosis and cytokinesis to yield 2 genetically identical cells.

3. Meiosis

This pathway examines how the process of meiosis in a eukaryotic cell results in 4 genetically distinct, haploid cells. It also explores the consequences of errors during meiosis and provides a comparison of mitosis and meiosis.

Mendelian Inheritance

1. From Genotype to Phenotype

This pathway explores the connection between genotype and phenotype in the context of the flow of information within a cell from genes to proteins.

2. Mendelian Inheritance

This pathway examines Mendel’s landmark studies of pea plants that allowed him to discover the basic principles of heredity. Topics covered include different types of genetic crosses (specifically monohybrid, dihybrid, multihybrid, and reciprocal crosses, as well as testcrosses), the concept of dominance, and Mendel’s laws of segregation and independent assortment. It also explores the use of branch diagrams and the rules of probability to solve genetic crosses.

Non-Mendelian Inheritance

1. One Gene, Multiple Factors

This pathway explores factors that act at individual loci and can alter the phenotypic ratios that Mendel’s principles predict. These factors include different types of dominance relationships, multiple alleles, pleiotropy, lethal alleles, penetrance, and expressivity.

2. Multiple Genes, One Phenotype

This pathway examines different types of interactions between genes at different loci that can contribute to the determination of a single phenotypic characteristic, specifically additive gene interactions and epistatic gene interactions.

‍

Explore more clusters in the LabXchange library!